I've just checked in an important performance related change for CocosDenshion. Basically Apple's recommendation for best OpenAL performance is to have all your audio samples at the same sample rate and to set the audio mixer to the same rate.
The default sample rate is 44100 Hz, however, if you need better performance it is recommended to use 22050 assuming you are happy with the sound quality. To use 22050 Hz execute the following code before any other audio code. This works with SimpleAudioEngine and CDAudioManager.
[CDSoundEngine setMixerSampleRate:CD_SAMPLE_RATE_MID];
Finally, CocosDenshion now has a CDConfig.h file that is analogous to cocos2d's ccConfig.h file. You can configure CocosDenshion using this file, importantly there is a CD_DEBUG define that is off by default - when it is enabled CocosDenshion will check and warn you about various things including whether it loads any files whose sample rate does not match the mixer sample rate.